HSQC with Real Time Acquisition Pure Shift

This pulse sequence version is obsolete (Oct, 2017).
New version is available.

Pure Shift NMR Spectroscopy suppresses the effects of homonuclear coupling, allowing 1H13C and 1H15N HSQC spectra to be produced that contain chemical shift only, with no multiplet structure, in both dimensions a major improvement in resolution.


Varian / Agilent
Pulse Sequence packages:
rtps_gHSQC_BIRD pulse sequence c file (right click and chose 'save ... as')
Parameter file zip (right click and chose 'save ... as')
Example data set zip (right click and chose 'save ... as')

Pulse sequence: pushhsqcrtbird (right click and chose 'save ... as')
Example data set (glucose) zip

Pulse Sequence Diagram:

Simultaneously enhancing spectral resolution and sensitivity in heteronuclear correlation NMR
Paudel, L.; Adams, R.W.; Kiraly, P.; Aguilar, J.A.; Foroozandeh, M.; Cliff, M.J.; Nilsson, M.; Sandor, P.; Waltho, J.P.; Morris, G.A.
Angew. Chem. Int. Ed. 2013, 52, 11616-11619

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