An ultra-selective 1D NMR experiment – GEMSTONE-ROESY – enables clear, unambiguous assignment of ROE signals in the not uncommon situation that traditional selective methods fail.

Bruker pulse sequences:
GEMSTONE-ROESY (right click and chose 'save ... as')

Example data:

Pulse Sequence Diagrams:

Ultra-selective, ultra-clean 1D rotating-frame Overhauser effect spectroscopy
Gates EL, Smith M, Bradley J, Johnson M, Widmalm G, Nilsson M, Morris GM, Adams RW, Castanar L.
Chem. Commun. 2023, 59, 5854 - 5857 (DOI: 10.1039/D3CC00550J).

GEMSTONE: Needles from haystacks: single‐scan selective excitation of individual NMR signals in overlapping multiplets
Kiraly P, Kern N, Plesniak MP, Nilsson M,Procter DJ, Morris GM, Adams RW.
Angew. Chem. Int. Ed., 2021, 60, 666-669.

Please note that copyright restrictions prevent us from placing the pdf files on our website, however, all articles are published open access and can be downloaded from the respective publishers.