Manchester NMR Methodology Group

Visiting Graduate Student
Christoffer.durieuxskoven@manchester.ac.uk

ORCID: https://orcid.org/0000-0002-9535-4359

G.020
Dover Street Building
Department of Chemistry
The University of Manchester
Manchester
M13 9PL

Research
Chemical Ecology application of NMR spectroscopy

Biography
I became a BSc in Chemistry and Technology in 2021 from the Technical University of Denmark. My bachelor’s thesis was titled “Purification and Structure Elucidation of Fungal Natural Products” under the supervision of Professors Charlotte Held Gotfredsen and Thomas Ostenfeld Larsen. During the project, I developed skills in LC-DAD-MS/MS-guided compound purification and discovered a strong interest in elucidating novel complex structures using NMR spectroscopy.

I graduated as an MSc in Applied Chemistry in 2023 from the Technical University of Denmark. For my master’s thesis I did an industry collaboration with Novo Nordisk CMC Analytical support titled “Exploring the Structures of Therapeutic siRNA in Drug Discovery”. The project focused on MS/MS- and NMR-based characterization of synthetic RNA oligomers, implementing advanced techniques such as JR-NOESY and ¹H-¹⁵N SOFAST-HMQC. The project was jointly supervised by Professor Charlotte Held Gotfredsen and principal scientist Joan Malmstrøm.

My Ph.D. project is a part of CeMiSt, a Centre of Excellence funded by the Danish National Research Foundation by the DNRF137 grant. The project is supervised by Professors Charlotte Held Gotfredsen and Lone Gram. The research centre studies the roles and functions of secondary metabolites in natural microbial systems. I am currently working on projects that involve quantifying, characterising and studying the biotransformation of natural products produced by Phaeobacter spp. In addition, I am also looking into the implementation of multivariate statistical analysis of NMR spectroscopic data. During my visit at the University of Manchester NMR Methodology group, I will contribute to research in complex mixture analysis and learn to implement these methods for my Ph.D. project under the supervision of Prof. Mathias Nilsson.